I finally uploaded ALL my work from college and client to my new portfolio gallery. I am using Zenphoto and I LOVE it! I totally recommend using it for a gallery managing system. It was relatively easy to set up and it makes it a lot easier to upload images without having to deal with code! Amazing. It utilizes MYSQL database and PHP so make sure your domain can support that. You can also upload .zips and .mov, .mp3 and .mp4. Yippie.
Its totally customizable too. I just figured out the PHP structure of the site and figured out the basic structure of the layout theme and CSS and just put my own CSS into the style.css file and assigned the right labels to the right divs, etc and done!
Def recommend it.